ABSTRACT
Purpose: Visual functioning evaluated by the Catquest?9SF questionnaire has shown to be a valid measure for assessing a patient抯 prioritization for cataract surgery. This study adapted Catquest?9SF for visual function outcomes post uni?lateral cataract surgery or bi?lateral cataract surgery. Methods: Visual functioning was assessed before and after uni?lateral or bi?lateral cataract surgery using the Catquest?9SF questionnaire. Patients were enrolled to this study prior to their cataract surgery between March 29 and April 30, 2021 at Shellharbour Hospital, Australia. Catquest?9SF questionnaires were completed prior to and 3 months post surgery. Resulting data were assessed for fit to a Rasch model using WINSTEPS software (version 4.2.0). Catquest?9SF data analysis of Chi?square, Wilcoxon sum test, and Fischer抯 test were performed in R (version 4.1.0). P value <.05 was considered statistically significant. Results: Sixty?one patients (mean age = 73.2 years, 62% female) were included for analysis. Catquest?9SF response thresholds, adequate precision (person separation index = 2.58, person reliability = 0.87, Cronbach抯 alpha = 0.74), uni?dimensionality, and no misfits (infit range 0.65�33; outfit range 0.64�31) were recorded. The mean of item calibration for patients was ?0.22 post?operatively. There was significant (P <.05) improvement (16.3%) in visual functions across all nine Catquest 9?SF items. There was a significant mean visual function difference between patients with uni?lateral (10.1%) and bi?lateral cataract surgery (22.3%) pre?operatively and post?operatively. Conclusion: The Catquest?9SF questionnaire showed excellent psychometric properties and can assess visual functioning in an Australian population. There was a significant improvement in patient visual function post cataract surgery and higher functioning with bi?lateral cataract surgery
ABSTRACT
Objective: To evaluate the protective role of leaves of Moringa oleifera (M. oleifera) Lam. against arsenic-induced toxicity in mice.Methods:non-treated control group while, the second, third, and fourth groups were treated with M.oleifera leaves (50 mg/kg body weight per day), sodium arsenite (10 mg/kg body weight per day) and sodium arsenite plus M. oleifera leaves, respectively. Serum indices related to cardiac, liver and renal functions were analyzed to evaluate the protective effect of Moringa leaves on arsenic-induced effects in mice.Results:Swiss albino male mice were divided into four groups. The first group was used as induced elevation of triglyceride, glucose, urea and the activities of alkaline phospatase, aspartate aminotransferase and alanine aminotransferase in serum. M. oleifera leaves also prevented the arsenic-induced perturbation of serum butyryl cholinesterase activity, total cholesterol and high density lipoprotein cholesterol.Conclusions:The results indicate that the leaves of M. oleifera may be useful in reducing the It revealed that food supplementation of M. oleifera leaves abrogated the arsenic-effects of arsenic-induced toxicity.